Slide 16 of 25
Notes:
Usually in the research one asks: How does the structure X look like before some kind of intervention (or before it was fully developed) or etc.. and what happens after? What kind of changes occur? These changes are preferably needed to be evaluated quantitatively.
And here the problem of unbiased estimation of parameters arises. The solution for it was introduced in the sixties - and was called stereology. Stereology is a set of tools and approaches for very fast and unbiased evaluation of number and size of structures of interest through their images on two-dimensional sections.